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Serious dermatological reactions, including stevens-johnson syndrome sjs and toxic epidermal necrolysis ten , have been reported in both children and adults in association with trileptal use.

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john s wort; tacrolimus prograf ; an antidepressant such as nefazodone; antifungal medication such as clotrimazole mycelex troche , itraconazole sporanox , ketoconazole extina, ketozole, nizoral, xolegal , or voriconazole vfend ; a barbiturate such as phenobarbital solfoton and others; heart or blood pressure medication such as diltiazem cartia, cardizem , felodipine plendil , nifedipine nifedical, procardia , verapamil calan, covera, isoptin, verelan , and others; hiv medication such as atazanavir reyataz , delavirdine rescriptor , efavirenz sustiva , etravirine intelence , fosamprenavir lexiva , indinavir crixivan , nelfinavir viracept , nevirapine viramune , saquinavir invirase , or ritonavir norvir ; or seizure medication such as carbamazepine carbatrol, tegretol , felbamate felbatol , oxcarbazepine trileptal , phenobarbital solfoton , phenytoin dilantin , or primidone mysoline .

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the authors said better studies are needed to determine whether trileptal is truly effective in bipolar disorder.

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controlled trials in these patients examined the effectiveness of a 1200 mg day dose; a dose of 2400 mg day has been shown to be effective in patients converted from other aeds to trileptal monotherapy see above .

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do not drive or operate machinery until you know how trileptal affects you.

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