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we generally wait until the urine is grossly clear for 24 hours before resuming warfarin, but we recommend confirming that the urine is grossly clear for at least 48 hours before restarting clopidogrel or aspirin because of the longer half-life of these agents and the inability to easily reverse them, if needed.

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clopidogrel minor atorvastatin has been reported to attenuate the antiplatelet activity of clopidogrel potentially by inhibiting cyp3a4 metabolism to its active metabolite; however, conflicting data exists.

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